The antimicrobial principle of ChitoSante®.jpg)
Chitosan is a well-known natural antibacterial agent and is used widely in household, agriculture, healthcare, and industry products. To increase the effectiveness and the usage of chitosan, VA&G Bioscience Inc. has successfully developed a breakthrough technology to produce bioactive ChitoSante, a special antimicrobial agent with chitosan and special fruit extract as its active ingredients. The molecular structure of chitosan is very similar to that of cellulose. -The difference between cellulose and chitosan is in their functional groups. R: hydroxyl (OH) for cellulose and amino (NH²) for chitosan. Amino is capable of antimicrobial.
The biochemical mechanisms of the antimicrobial effect for ChitoSante® are as follows:
Chitosante® with Chitosan is its ingredient is cationic and can neutralize anionic phospholipids on the wall of a bacterial cell, then destroy the permeability of the cell membrane, and can cause cytoplasm to flow out of the bacterial cell, resulting in the death of the bacteria.
Chitosan in Chitosante® consists of highly bioactive oligosaccharides and can penetrate a bacteria cell to suppress the transformation of DNA to RNA and prevent the growth of bacteria cells.
Chitosan also reacts with special natural fruit extract in ChitoSante® to significantly increase the bioactivity and cations presented in ChitoSante®. Therefore, ChitoSante® can interact with the sialic acid in the cell wall of fungi to effectively suppress cell growth and the cross-linking between polysaccharide and peptide in Fungi.
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The antimicrobial effects of ChitoSante®:
The antimicrobial effects of ChitoSante® have been successfully tested using the methods of US AATCC-Test Method 147-1993, the Japanese JIS L1902-2002 and the Chinese GB 15979-2002. The test results on staphylococcus aureus (ATCC No.6538) obtained by the AATTCC-test method 147 as shown below:
Samples: Fabric with ChitoSante and a control sample without ChitoSante
Results: A bacteria-free zone can clearly be seen on the fabric sample (right).
